Biotin: Benefits, Side Effects, Dosage, and Interactions - Verywell Health
Biotin (vitamin B7) is an essential micronutrient that's important for energy production and other functions in your body. It is found in foods like oats and egg yolks and can also be taken in supplement form.
Biotin supplements and shampoos are often promoted for improving hair health and regrowing lost hair. However, research suggests they're only effective in people whose hair problems are caused by a biotin deficiency.
This article discusses the possible benefits of biotin for your health and hair, its possible side effects and safety information, the proper dosage, and how to select the right biotin product for you.
Verywell / JR Bee
What Is Biotin?
Biotin is an essential vitamin—meaning your body needs it to function properly but doesn't produce it on its own. You need to get biotin from your diet or supplements.
Biotin helps your body:
- Turn dietary protein, carbohydrates, and fat into energy
- Regulate signals sent by your cells
- Regulate the activity of your genes
Biotin is available in many common foods and you don't need a lot of it.
Biotin Supplement Benefits
Biotin is often mentioned in the context of hair loss treatment. Despite this, research backing up such a benefit is scant. The same goes for other possible benefits of biotin.
Where biotin supplementation is likely effective is in the treatment of biotin deficiency. This, however, is rare in the United States.
If you're not deficient in biotin, taking a supplement would likely offer no benefits.
Hair Growth
Some proponents claim that biotin-containing products can make your hair thicker, stronger, shinier, and more voluminous. Science doesn't support these claims.
A handful of research studies have shown that biotin supplementation may help stimulate hair regrowth in people who have a clinical biotin deficiency or alopecia (hair loss).
In people with temporary hair loss, studies have shown that supplements containing biotin significantly improved hair growth after 90 days. Some case reports suggests biotin supplementation is beneficial for people who have an underlying medical condition causing their hair to thin.
Even so, researchers also note that hair regrowth is often caused by many factors and may not be due to biotin supplementation at all.
Other Purported Benefits
Other possible benefits of biotin include treating:
However, the evidence that biotin can treat any of these conditions is insufficient.
Do You Need More Biotin?
Though biotin deficiency is not common in the U.S., it does occur. Certain health conditions, medications, and lifestyle choices can make someone prone to a deficiency.
A healthcare provider can diagnose a biotin deficiency with lab work. Biotin supplementation and/or dietary increases may be an important part of correcting the deficiency.
Symptoms of Biotin Deficiency
Symptoms of a biotin deficiency include:
- Thinning hair
- Brittle nails
- Dry skin
- A red, scaly rash, usually around the eyes, nose, and mouth
- Conjunctivitis (pink eye)
- Depression
- Exhaustion
- Hallucinations
- Numbness and tingling in your arms and legs
If you notice any symptoms of biotin deficiency, see your healthcare provider for a diagnosis. Many other things can cause similar symptoms but require different treatments.
Causes and Risk Factors
You are more likely to experience biotin deficiency if you:
- Consume a lot of raw egg whites, such as in smoothies: Uncooked eggs contain a protein called avidin, which blocks the absorption of biotin.
- Have inflammatory bowel disease or other conditions involving an imbalance of intestinal bacteria
- Drink a lot of alcohol or have cirrhosis (a liver disease often related to alcohol)
- Have the rare genetic disorder biotinidase deficiency, which prevents biotin absorption
Medications that can lead to biotin deficiency include:
- Beta-blockers (blood pressure medications)
- Blood thinners
- Anticonvulsants (seizure/epilepsy medications)
- Retinoids (topical medications for acne and reducing wrinkles)
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Possible Biotin Side Effects
Biotin supplements can cause problems if you take too much. Side effects of biotin can include:
- Trouble sleeping
- Skin rashes
- Digestive upset
- Problems with insulin release
- Kidney problems
According to a report published in the New England Journal of Medicine, biotin treatment was said to interfere with laboratory tests and mimic Graves' disease—a condition that causes the thyroid to produce too much thyroid hormone.
As with any supplement, the safety of long-term or high-dose use isn't known. Always check with your healthcare provider before starting a supplement regimen.
Dosage and Safety
The Food and Drug Administration (FDA) has not established a recommended dietary allowance (RDA) for biotin.
According to the National Institutes of Health (NIH), 30 micrograms (mcg) is the adequate daily intake for adults 19 years of age and older. People can usually get this amount through their diet.
Still, people who support its use often recommend taking 2 to 5 milligrams (mg) of biotin in supplement form daily in order to strengthen hair and achieve results.
Although biotin is a water-soluble vitamin (meaning any excess comes out in your urine and feces), the safety of using any amount of biotin in supplement form is unknown.
As with many other supplements, biotin hasn't been tested for safety:
- During pregnancy and breastfeeding
- In children
- In people with chronic conditions
- In people taking medications
Don't take biotin supplements in lieu of getting medical attention. That can cause dangerous delays in getting a proper diagnosis and treatment.
What to Look For
Bacteria in the intestines usually provide more than the body's daily biotin requirements, and many foods contain biotin as well.
If you're diagnosed with a deficiency, you can correct it with supplements, a biotin-rich diet, or both.
Biotin Supplements
In the United States, supplements are largely unregulated and aren't always tested for quality. That means the content of a product may not match what's on the label.
To ensure you're getting what's on the label, look for supplements that have been voluntarily submitted for testing by an independent certifying body such as:
- U.S. Pharmacopeia (USP)
- ConsumerLab
- NSF International
Certification means the label is correct and the product isn't contaminated. It doesn't guarantee safety or effectiveness. Always talk to your healthcare provider before taking a new supplement.
Biotin-Rich Foods
Food sources of biotin (in micrograms per 100 grams) include:
- Cooked egg yolks (53)
- Oats (27.0)
- Wheat germ (17.0)
- White mushrooms (16)
- Spinach (6.9)
- Cheese, brie (6.2)
- Milk (3.5)
- Pork (5.0)
- Carrot (5.0)
- Apple (4.5)
- Tomato (4.0)
- Beef (3.0)
- Chicken (2.0)
- Lettuce (1.9)
Summary
There's not enough evidence to prove that biotin supplements are safe or effective for hair thinning or loss.
If you're concerned about your hair health for any reason, talk to your healthcare provider. If you have a biotin deficiency, you can correct it through diet or supplements.
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